The bioaccumulation of hexavalent uranium (U(VI)) on Candida utilis (C. utilis) and its biological effects were investigated via batch and biologic techniques. The bioaccumulation mechanism of U(VI) and C. utilis were characterized by SEM, TEM, FT-IR and XPS. The batch results showed that C. utilis had a high adsorption capacity (41.15 mg/g wet cells at pH 5.0) and high equilibrium rate (~100% within 3.5 h). The analysis of intracellular hydrogen peroxides and malondialdehyde suggested that the growth of C. utilis was inhibited under different concentrations of U(VI) due to the abundant production of reactive oxide species. The activity of intracellular antioxidants (e.g., super oxide dismutase and glutathione) was significantly enhanced under U(VI) stress, indicating the anti-toxic effect of C. utilis cells under low U(VI) stress. These results indicated that C. utilis is an ideal biosorbent for removing radionuclides in environmental remediation.

通过分批和生物学技术研究了六价铀（U（VI））在假丝酵母（C. utilis）上的生物富集及其生物学效应。通过SEM，TEM，FT-IR和XPS对U（VI）和util鱼的生物富集机理进行了表征。批处理结果显示，鱼梭菌具有较高的吸附能力（pH 5.0时为41.15 mg / g湿细胞）和较高的平衡速率（3.5 h内约100％）。细胞内过氧化氢和丙二醛的分析表明，C。utilis的生长由于大量生产的活性氧化物，在不同浓度的U（VI）时会抑制H2O3。胞内抗氧化剂（例如，超氧化物歧化酶和谷胱甘肽）的活性U（Ⅵ）的应力下显著增强，表明的抗中毒效果C.刺细胞低U（Ⅵ）的压力。这些结果表明，util。C. utilis是去除环境中放射性核素的理想生物吸附剂。