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Paget’s Disease of the Bone: Patterns of Referral to Secondary Care Following Diagnosis on X-rays
Calcified Tissue International ( IF 3.3 ) Pub Date : 2021-01-02 , DOI: 10.1007/s00223-020-00800-5
Julie A Walker 1 , Stephen Paul Tuck 2
Affiliation  

Paget’s disease of bone (PDB) is the second commonest metabolic bone disorder in the UK after osteoporosis and is both underdiagnosed and undertreated. PDB is often found incidentally on plain X-rays. There is effective treatment so identification of affected individuals is important. The aim was to conduct an audit to determine what proportion of individuals with X-ray evidence of PDB were referred to secondary care. A retrospective audit of X-rays reports in men and women over 55 years of age was undertaken over 18 months searching for the key word “Paget’s.” The images of possible cases were reviewed and the presence of PDB confirmed. The proportion already known to secondary care was determined and those that had had isotope bone scans and treatment. Data recorded included site of lesion, age, gender, level of total alkaline phosphatase (ALP) and complications. A total of 68,873 X-rays were screened and 43 cases found. Pelvic images had the highest proportion of positive findings at 0.2% and 65% of the cases. 74% had not been referred to secondary care. The mean age was 86.7 years (range 65–95) and the ALP was elevated in 65% with a mean of 189u/L (range 47–804u/L). In 33 individuals, PDB had been recorded in the reports of previous X-rays. The rate of referral for specialist care remains low. The prevalence of the condition appears to be falling.



中文翻译:

佩吉特骨病:X 射线诊断后转诊至二级护理的模式

佩吉特骨病 (PDB) 是继骨质疏松症之后英国第二常见的代谢性骨病,诊断不足和治疗不足。PDB 经常在普通 X 光片上偶然发现。有有效的治疗方法,因此识别受影响的个体很重要。目的是进行审计以确定有多少比例的有 PDB 的 X 射线证据的个人被转介到二级保健。在 18 个月内对 55 岁以上男性和女性的 X 射线报告进行了回顾性审核,以寻找关键词“佩吉特”。审查了可能病例的图像,并确认了 PDB 的存在。已确定二级保健已知的比例以及已进行同位素骨扫描和治疗的比例。记录的数据包括病变部位、年龄、性别、总碱性磷酸酶(ALP)水平和并发症。共筛查了68873张X光片,发现了43例。盆腔图像的阳性结果比例最高,分别为 0.2% 和 65%。74% 没有被转介到二级保健。平均年龄为 86.7 岁(范围 65-95),ALP 升高 65%,平均为 189u/L(范围 47-804u/L)。在 33 个人中,PDB 已记录在以前的 X 射线报告中。专科护理的转诊率仍然很低。这种情况的患病率似乎正在下降。7 年(范围 65-95),ALP 升高 65%,平均值为 189u/L(范围 47-804u/L)。在 33 个人中,PDB 已记录在以前的 X 射线报告中。专科护理的转诊率仍然很低。这种情况的患病率似乎正在下降。7 年(范围 65-95),ALP 升高 65%,平均值为 189u/L(范围 47-804u/L)。在 33 个人中,PDB 已记录在以前的 X 射线报告中。专科护理的转诊率仍然很低。这种情况的患病率似乎正在下降。

更新日期:2021-01-03
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