Amano lipase AK from P. fluorescens was immobilized on different types of chitosan-containing supports. Chitosan lower molecular weight (2.5%), chitosan lower molecular weight/sodium alginate (2.5%/2.5%) and chitosan lower molecular weight/carrageenan (2.5%/2.5%) allowed the highest values of immobilization yields (IY) of 81, 81 and 83%, respectively. Best activity results were achieved using chitosan average molecular weight (5%) and chitosan lower molecular weight/sodium alginate (2.5%/2.5%) as support, with values of 1.40 and 1.30 U_pNPB/g_gel and with recovery activities of 45.75 and 35.6%, respectively. These derivatives were evaluated in the kinetic resolution of rac-indanol to obtain a key intermediate in the synthesis of a drug used in the treatment of Parkinson's disease. The most efficient derivatives in the kinetic resolution were lipase immobilized on chitosan average molecular weight (5.0%) and chitosan low molecular weight/sodium alginate, the latter leading to obtaining both (S)-indanol and (R)-indanyl acetate with > 99% ee and 50% conversion.

来自荧光假单胞菌的天野脂肪酶 AK固定在不同类型的含壳聚糖载体上。壳聚糖低分子量 (2.5%)、壳聚糖低分子量 / 海藻酸钠 (2.5% / 2.5%) 和壳聚糖低分子量 / 角叉菜胶 (2.5% / 2.5%) 允许固定化产率 (IY) 的最高值分别为 81、81 和 83%。使用壳聚糖平均分子量（5%）和壳聚糖低分子量/海藻酸钠（2.5%/2.5%）作为载体获得最佳活性结果，值分别为1.40和1.30 U _{p NPB} /g_凝胶，并具有回收活性分别为 45.75 和 35.6%。这些衍生物在rac的动力学拆分中进行了评估- 茚满醇获得合成用于治疗帕金森病的药物的关键中间体。动力学拆分中最有效的衍生物是固定在壳聚糖平均分子量 (5.0%) 上的脂肪酶和壳聚糖低分子量/海藻酸钠，后者导致获得 ( S ) -茚满醇和 ( R ) - 乙酸茚满酯 > 99 % ee和 50% 转化率。