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The Effect of Partnership Presence and Support on HIV Viral Suppression Among Serodiscordant Partnered and Single Heterosexual HIV-Positive Individuals in Brazil
AIDS and Behavior ( IF 2.7 ) Pub Date : 2021-01-02 , DOI: 10.1007/s10461-020-03124-5
Zoë Baker 1 , Pamina Gorbach 2 , Marineide Gonçalves de Melo 3 , Ivana Varela 3 , Eduardo Sprinz 3 , Breno Santos 3 , Tauí de Melo Rocha 3 , Mariana Simon 3 , Marcelo Almeida 3 , Rita Lira 3 , Maria Cristina Chaves 3 , Tara Kerin 4 , Karin Nielsen-Saines 4
Affiliation  

HIV-negative individuals in serodiscordant partnerships experience reduced risk of HIV acquisition when their partners adhere to ART and achieve undetectable viral loads. Partnership support may encourage ART adherence, reducing viral load and the risk of HIV transmission. This study aims to determine whether HIV viral suppression is associated with partnership status and partnership support among 201 HIV positive (HIV+ individuals in serodiscordant partnerships and 100 HIV+ unpartnered individuals receiving care at Hospital Nossa Senhora da Conceição in Porto Alegre, Brazil between 2014 and 2016. Clinical data and patient-reported questionnaire data were assessed, and propensity scores were used to control for confounding variables in adjusted logistic regression models. Viral suppression did not significantly differ between HIV+ partnered (78.5% virally suppressed) and unpartnered (76.0% virally suppressed) individuals. Among individuals in partnerships, viral suppression was significantly associated with having a partner who attended monthly clinic visits (AOR 2.99; 95% CI 1.00–8.93). Instrumental social support—attending monthly visits—may improve the odds of viral suppression among HIV+ individuals in serodiscordant relationships.



中文翻译:

伙伴关系的存在和支持​​对巴西血清不一致伙伴和单身异性恋 HIV 阳性个体 HIV 病毒抑制的影响

当伴侣坚持抗逆转录病毒治疗并达到检测不到的病毒载量时,血清不一致伴侣关系中的 HIV 阴性个体感染 HIV 的风险会降低。伙伴关系支持可以鼓励 ART 依从性,减少病毒载量和 HIV 传播的风险。本研究旨在确定 2014 至 2016 年间在巴西阿雷格里港的 Nossa Senhora da Conceição 医院接受护理的 201 名 HIV 阳性(伴侣关系不一致的 HIV+ 个体和 100 名 HIV+ 无伴侣个体)之间的 HIV 病毒抑制是否与伙伴关系状态和伙伴关系支持相关。评估了临床数据和患者报告的问卷数据,并使用倾向评分来控制调整后的逻辑回归模型中的混杂变量。病毒抑制在 HIV+ 伴侣之间没有显着差异 (78. 5% 病毒抑制)和无伴侣(76.0% 病毒抑制)个体。在伙伴关系中的个体中,病毒抑制与伴侣每月就诊一次显着相关(AOR 2.99;95% CI 1.00–8.93)。工具性的社会支持——参加每月的访问——可能会提高处于血清不一致关系中的 HIV+ 个体中病毒抑制的几率。

更新日期:2021-01-03
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