Uncomplicated Enterobacteriaceae bacteremia is usually transient and may not require follow-up blood cultures (FUBC). This is a retrospective observational study conducted at a university-affiliated urban teaching hospital in Seattle, WA. All patients ≥ 18 years hospitalized between July 2014 and August 2019 with ≥ 1 positive blood culture for either Escherichia coli or Klebsiella species were included. The primary outcome was to determine the number and frequency of FUBC obtained, and the detection rate for positive FUBC. There were 335 episodes of E. coli and Klebsiella spp. bacteremia with genitourinary (54%) being the most common source. FUBC were sent in 299 (89.3%) patients, with a median of 3 (interquartile range (IQR): 2, 4) sets of FUBC drawn per patient. Persistent bacteremia occurred in 37 (12.4%) patients. In uncomplicated E. coli and Klebsiella spp. bacteremia, when the pre-test probability of persistent bacteremia is relatively low, FUBC may not be necessary in the absence of predisposing factors.

简单的肠杆菌科菌血症通常是暂时性的，可能不需要后续血培养 (FUBC)。这是在华盛顿州西雅图市的一家大学附属城市教学医院进行的回顾性观察研究。包括所有在 2014 年 7 月至 2019 年 8 月期间住院且血培养 ≥ 1 次大肠杆菌或克雷伯菌属阳性的患者 ≥ 18 岁。主要结果是确定获得的 FUBC 的数量和频率，以及阳性 FUBC 的检出率。有 335 集大肠杆菌和克雷伯氏菌属 泌尿生殖系统的菌血症 (54%) 是最常见的来源。FUBC 在 299 (89.3%) 名患者中发送，每名患者抽取 FUBC 的中位数为 3（四分位距 (IQR)：2、4）组。37 名 (12.4%) 患者出现持续性菌血症。在简单的大肠杆菌和克雷伯氏菌中。菌血症，当持续性菌血症的预检概率相对较低时，在没有诱发因素的情况下，FUBC可能是不必要的。