Chromatophores of purple non-sulfur bacteria (PNSB) are invaginations of the cytoplasmic membrane that contain a relatively simple system of light-harvesting protein–pigment complexes, a photosynthetic reaction center (RC), a cytochrome complex, and ATP synthase, which transform light energy into the energy of synthesized ATP. The high content of negatively charged phosphatidylglycerol (PG) and cardiolipin (CL) in PNSB chromatophore membranes makes these structures potential targets that bind cationic antiseptics. We used the methods of stationary and kinetic fluorescence spectroscopy to study the effect of some cationic antiseptics (chlorhexidine, picloxydine, miramistin, and octenidine at concentrations up to 100 μM) on the spectral and kinetic characteristics of the components of the photosynthetic apparatus of Rhodobacter sphaeroides chromatophores. Here we present the experimental data on the reduced efficiency of light energy conversion in the chromatophore membranes isolated from the photosynthetic bacterium Rb. sphaeroides in the presence of cationic antiseptics. The addition of antiseptics did not affect the energy transfer between the light-harvesting LH1 complex and reaction center (RC). However, it significantly reduced the efficiency of the interaction between the LH2 and LH1 complexes. The effect was maximal with 100 μM octenidine. It has been proved that molecules of cationic antiseptics, which apparently bind to the heads of negatively charged cardiolipin molecules located in the rings of light-harvesting pigments on the cytoplasmic surface of the chromatophores, can disturb the optimal conditions for efficient energy migration in chromatophore membranes.

紫色非硫细菌 (PNSB) 的色素细胞是细胞质膜的内陷，其中包含一个相对简单的捕光蛋白 - 色素复合物系统、一个光合反应中心 (RC)、一个细胞色素复合物和 ATP 合酶，这些系统将光转化为能量转化为合成ATP的能量。PNSB 色素细胞膜中带负电荷的磷脂酰甘油 (PG) 和心磷脂 (CL) 的高含量使这些结构成为结合阳离子防腐剂的潜在目标。我们使用静态和动态荧光光谱法研究了一些阳离子防腐剂（浓度高达 100 μM 的氯己定、匹克昔定、米拉米斯汀和奥替尼丁）对光合装置组件的光谱和动力学特性的影响。球形红细菌色素细胞。在这里，我们展示了从光合细菌Rb分离的色素细胞膜中光能转换效率降低的实验数据。球状体在阳离子防腐剂的存在下。添加防腐剂不影响光捕获 LH1 复合物和反应中心 (RC) 之间的能量转移。然而，它显着降低了 LH2 和 LH1 复合物之间相互作用的效率。使用 100 μM 奥替尼啶时效果最大。已经证明，阳离子防腐剂分子显然与位于色素细胞细胞质表面的捕光色素环中的带负电荷的心磷脂分子的头部结合，可以干扰色素细胞膜中有效能量迁移的最佳条件.