The role of pharmacists in the treatment of HIV has expanded beyond medication dispensing to include a host of cost-effective, evidence-based strategies across the HIV prevention and care continuums. However, wide-scale adoption of pharmacy-based HIV prevention and treatment interventions has been slow. We conducted a systematic review to evaluate the evidence on the role of pharmacists across the HIV prevention and care continuums. Thirty-two studies were identified, most of which provided evidence of feasibility of HIV testing and efficacy of non-prescription syringe sale services in pharmacies. However, only two studies implemented an experimental design to rigorously test pharmacy-based strategies. Notably, no pharmacy-based strategies have specifically targeted the highest HIV risk populations such as black and Latinx men who have sex with men, women, or trans populations. Efficacy trials and effectiveness studies should rigorously test existing pharmacy-based strategies to build greater support for wide-scale adoption and implementation. Moreover, in order to integrate pharmacies into the strategy to end the HIV epidemic, studies are needed to ensure that pharmacy-based HIV prevention and treatment services can reach the highest risk populations.

药剂师在 HIV 治疗中的作用已超出药物配药范围，包括一系列具有成本效益的循证策略，贯穿 HIV 预防和护理的连续统一体。然而，大规模采用基于药学的 HIV 预防和治疗干预措施进展缓慢。我们进行了系统评价，以评估药剂师在整个 HIV 预防和护理过程中的作用的证据。确定了 32 项研究，其中大部分提供了 HIV 检测的可行性和药店非处方注射器销售服务有效性的证据。然而，只有两项研究实施了实验设计来严格测试基于药学的策略。尤其，没有基于药房的策略专门针对艾滋病毒风险最高的人群，例如与男性、女性或跨性别人群发生性关系的黑人和拉丁裔男性。功效试验和有效性研究应严格测试现有的基于药学的策略，为大规模采用和实施提供更大的支持。此外，为了将药房纳入结束艾滋病流行的战略，需要开展研究以确保以药房为基础的艾滋病毒预防和治疗服务能够覆盖最高风险人群。