This paper presents the first wireless and programmable neural stimulator leveraging magnetoelectric (ME) effects for power and data transfer. Thanks to low tissue absorption, low misalignment sensitivity and high power transfer efficiency, the ME effect enables safe delivery of high power levels (a few milliwatts) at low resonant frequencies ( $\sim$ 250 kHz) to mm-sized implants deep inside the body (30-mm depth). The presented MagNI (Magnetoelectric Neural Implant) consists of a 1.5-mm $^2$ 180-nm CMOS chip, an in-house built 4 × 2 mm ME film, an energy storage capacitor, and on-board electrodes on a flexible polyimide substrate with a total volume of 8.2 mm $^3$ . The chip with a power consumption of 23.7 $\mu$ W includes robust system control and data recovery mechanisms under source amplitude variations (1-V variation tolerance). The system delivers fully-programmable bi-phasic current-controlled stimulation with patterns covering 0.05-to-1.5-mA amplitude, 64-to-512- $\mu$ s pulse width, and 0-to-200-Hz repetition frequency for neurostimulation.

中文翻译：

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MagNI：磁电驱动和控制的无线神经刺激植入物


本文介绍了首款利用磁电 (ME) 效应进行电源和数据传输的无线可编程神经刺激器。由于组织吸收率低、错位敏感性低和功率传输效率高，ME 效应能够以低共振频率 ($\sim$ 250 kHz) 安全地将高功率水平（几毫瓦）传输到植入体深处的毫米级植入物。主体（30 毫米深度）。所展示的 MagNI（磁电神经植入物）由 1.5 毫米 $^2$ 180 纳米 CMOS 芯片、内部构建的 4 × 2 毫米 ME 薄膜、储能电容器和柔性聚酰亚胺上的板载电极组成总体积为 8.2 mm $^3$ 的基板。该芯片功耗为 23.7 $\mu$ W，在源幅度变化（1V 变化容差）下具有强大的系统控制和数据恢复机制。该系统提供完全可编程的双相电流控制刺激，其模式涵盖 0.05 至 1.5 mA 振幅、64 至 512 $\mu$ s 脉冲宽度和 0 至 200 Hz 重复频率，用于神经刺激。