Nanotechnology is a new frontier of this century that finds applications in various fields of science with important effects on our life and on the environment. Nanoencapsulation of bioactive compounds is a promising topic of nanotechnology. The excessive use of synthetic compounds with antifungal activity has led to the selection of resistant fungal species. In this context, the use of plant essential oils (EOs) with antifungal activity encapsulated in ecofriendly nanosystems could be a new and winning strategy to overcome the problem. We prepared nanoencapsules containing the essential oils of Origanum vulgare (OV) and Thymus capitatus (TC) by the nanoprecipitation method. The colloidal suspensions were characterized for size, polydispersity index (PDI), zeta potential, efficiency of encapsulation (EE) and loading capacity (LC). Finally, the essential oil nanosuspensions were assayed against a panel of fourteen fungal strains belonging to the Ascomycota and Basidiomycota phyla. Our results show that the nanosystems containing thyme and oregano essential oils were active against various fungal strains from natural environments and materials. In particular, the minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) values were two to four times lower than the pure essential oils. The aqueous, ecofriendly essential oil nanosuspensions with broad-spectrum antifungal activity could be a valid alternative to synthetic products, finding interesting applications in the agri-food and environmental fields.

中文翻译：

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具有增强的抗真菌活性的纳米胶囊精油，可能在农业食品，材料和环境领域中得到潜在应用

纳米技术是本世纪的一个新领域，它发现了在科学的各个领域中的应用，对我们的生活和环境产生了重要影响。生物活性化合物的纳米封装是纳米技术的一个有前途的话题。过度使用具有抗真菌活性的合成化合物导致了对抗性真菌物种的选择。在这种情况下，使用封装在环保纳米系统中的具有抗真菌活性的植物精油（EOs）可能是解决该问题的一种新的成功策略。我们制备了含有牛至叶精油和百里香百里香精油的纳米胶囊。（TC）通过纳米沉淀法。胶体悬浮液的尺寸，多分散指数（PDI），ζ电势，包封效率（EE）和负载容量（LC）被表征。最后，针对一组十四个属于子囊菌和担子菌门的真菌菌株，对精油纳米悬浮液进行了分析。我们的结果表明，包含百里香和牛至精油的纳米系统对天然环境和材料产生的各种真菌菌株具有活性。尤其是，最小抑菌浓度（MIC）和最小杀真菌浓度（MFC）值比纯精油低2-4倍。具有广谱抗真菌活性的水性，环保型精油纳米悬浮液可能是合成产品的有效替代品，