A new noninvasive glucose sensor is developed based on Co3O4 particles (Co3O4 NPs), which are synthesized by a single-step hydrothermal method with uniform structure and size. The electrochemical measurements reveal that the device exhibits outstanding performance for glucose detection, achieving a maximal sensitivity of 2495.79[Formula: see text][Formula: see text]A mM[Formula: see text] cm[Formula: see text] with a high [Formula: see text] of 0.99575, a ultra-low detection limit of 9.3[Formula: see text]nM with a signal-to-noise of 3 and linear range up to 3[Formula: see text]mM. The noninvasive glucose sensor can respond swiftly and selectively due to the high electrocatalytic activity of Co3O4 NPs. The sensor also shows its high sensitivity and selectivity in detecting glucose levels in human blood serum and saliva sample, confirming the application potential of Co3O4 NPs in noninvasive detection of glucose.

中文翻译：

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Co3O4 纳米颗粒作为唾液中葡萄糖检测的无创电化学传感器

基于Co的新型无创血糖传感器研制3○4颗粒（钴3○4NPs），它们是通过一步水热法合成的，具有均匀的结构和尺寸。电化学测量表明，该器件在葡萄糖检测方面表现出优异的性能，最高灵敏度达到2495.79[公式：见正文][公式：见正文]A mM[公式：见正文] cm[公式：见正文] [公式：见正文]为0.99575，超低检测限为9.3[公式：见正文]nM，信噪比为3，线性范围高达3[公式：见正文]mM。由于钴的高电催化活性，无创葡萄糖传感器可以快速和选择性地响应3○4NP。该传感器在检测人血清和唾液样本中的葡萄糖水平方面也表现出高灵敏度和选择性，证实了钴的应用潜力3○4NPs 在无创检测葡萄糖中的作用。