Infectious diseases are major threats to human health and lead to a serious public health burden. The emergence of new pathogens and the mutation of known pathogens challenge our ability to diagnose and control infectious diseases. Nanopore sequencing technology exhibited versatile applications in pathogenic microorganism detection due to its flexible data throughput. This review article introduced the applications of nanopore sequencing in clinical microbiology and infectious diseases management, including the monitoring of emerging infectious diseases outbreak, identification of pathogen drug resistance, and disease-related microbial communities characterization.

中文翻译：

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纳米孔测序技术在病原微生物检测中的应用

传染病是人类健康的重大威胁，造成严重的公共卫生负担。新病原体的出现和已知病原体的突变挑战了我们诊断和控制传染病的能力。纳米孔测序技术因其灵活的数据吞吐量而在病原微生物检测中展现出广泛的应用。本文介绍了纳米孔测序在临床微生物学和传染病管理中的应用，包括新发传染病疫情监测、病原体耐药性鉴定以及疾病相关微生物群落表征。