Horizontal gene transfer (HGT) is a major source of variability in prokaryotic genomes. Regions of genome plasticity (RGPs) are clusters of genes located in highly variable genomic regions. Most of them arise from HGT and correspond to genomic islands (GIs). The study of those regions at the species level has become increasingly difficult with the data deluge of genomes. To date, no methods are available to identify GIs using hundreds of genomes to explore their diversity.

中文翻译：

---

panRGP：一种基于全基因组的方法来预测基因组岛并探索其多样性

水平基因转移（HGT）是原核基因组变异的主要来源。基因组可塑性区域（RGP）是位于高度可变的基因组区域的基因簇。它们中的大多数来自HGT，并对应于基因岛。随着基因组数据的泛滥，在物种层面上对这些区域的研究变得越来越困难。迄今为止，尚无可用数百种基因组来探索GI的方法来识别GI。