当前位置: X-MOL 学术Bioinformatics › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Padhoc: a computational pipeline for pathway reconstruction on the fly
Bioinformatics ( IF 4.4 ) Pub Date : 2020-12-29 , DOI: 10.1093/bioinformatics/btaa811
Salvador Casaní-Galdón 1 , Cecile Pereira 2, 3 , Ana Conesa 2
Affiliation  

Molecular pathway databases represent cellular processes in a structured and standardized way. These databases support the community-wide utilization of pathway information in biological research and the computational analysis of high-throughput biochemical data. Although pathway databases are critical in genomics research, the fast progress of biomedical sciences prevents databases from staying up-to-date. Moreover, the compartmentalization of cellular reactions into defined pathways reflects arbitrary choices that might not always be aligned with the needs of the researcher. Today, no tool exists that allow the easy creation of user-defined pathway representations.

中文翻译:

Padhoc:动态重建路径的计算管道

分子途径数据库以结构化和标准化的方式表示细胞过程。这些数据库支持在生物学研究和高通量生化数据的计算分析中在社区范围内利用途径信息。尽管途径数据库在基因组学研究中至关重要,但是生物医学科学的快速发展阻止了数据库的更新。而且,将细胞反应分隔为确定的途径反映了任意选择,这些选择可能并不总是与研究者的需求相一致。如今,没有工具可以轻松创建用户定义的路径表示形式。
更新日期:2020-12-31
down
wechat
bug