Abstract

Considerable methods have so far been used for the surface modification of biomedical membranes. Several reviews and articles have been published on the improvements achieved in the field of poly(arylsulfone) membranes subjected to various surface modification methods and used in biomedical applications. This review concentrates on the surface modification, biological applications and future perspective of the poly(arylsulfone) biomedical membranes. Different surface modification procedures employed for the poly(arylsulfone) membranes have been classified, studied and compared. Diverse surface modification techniques include surface coating, chemical modification and immobilization/cross-linking, grafting, surface zwitterionicalization, mussel-inspired coating and layer-by-layer assembly. Furthermore, we review the recent research studies performed on the surface modification of the poly(arylsulfone) biomedical membranes. Meanwhile, the properties of biomedical membranes are also discussed in each section. At last, the future perspective and challenges of the strategies utilized for the surface modification of poly(arylsulfone) biomedical membranes are presented.

摘要

迄今为止，已经有相当多的方法用于生物医学膜的表面改性。已经发表了几篇关于在经过各种表面改性方法和用于生物医学应用的聚（芳基砜）膜领域取得的改进的评论和文章。本综述主要关注聚（芳基砜）生物医学膜的表面改性、生物学应用和未来前景。已对用于聚（芳基砜）膜的不同表面改性程序进行分类、研究和比较。多种表面改性技术包括表面涂层、化学改性和固定/交联、接枝、表面两性离子化、贻贝涂层和逐层组装。此外，我们回顾了最近对聚（芳基砜）生物医学膜的表面改性进行的研究。同时，每节还讨论了生物医学膜的特性。最后，提出了用于聚（芳基砜）生物医学膜表面改性策略的未来前景和挑战。