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Effect of particle morphology on performance of an electrostatic air–liquid interface cell exposure system for nanotoxicology studies
Nanotoxicology ( IF 3.6 ) Pub Date : 2020-12-30 , DOI: 10.1080/17435390.2020.1863499
Ta-Chih Hsiao, Hsiao-Chi Chuang, Jing-Chi Lin, Tsun-Jen Cheng, Li-Ti Chou

Abstract

Particle morphology can affect the performance of an electrostatic precipitator air–liquid interface (ESP-ALI) cell exposure system and the resulting cell toxicity. In this study, three types of monodisperse aerosols – spherical sucrose particles, nonspherical align soot aggregates, and nanosilver aggregates/agglomerates – were selected to evaluate the collection efficiency at flow rates ranging from 0.3 to 1.5 lpm. To quantify the particle morphology, the fractal dimensions (Df) of the tested aerosols were characterized. The penetration of fine particles (dp = 100–250nm) under different operating conditions was correlated with a characteristic exponential curve using the dimensionless drift velocity (Vc/Vavg,r) as the scaling parameter. For nanoparticles (NPs, dp <100nm) with different particle morphologies, the particle penetrations in the ESP-ALI were similar, but their diffusion losses were not negligible. In contrast, for fine particles, the collection efficiency of soot nanoaggregates (Df = 2.29) was higher than that of spherical sucrose particles. This difference might be due to the simultaneous influences of the electric field-induced and flow field-induced alignment. Furthermore, based on Zhibin and Guoquan’s Deutsch model, a quadratic equation was applied to fit the experimental data and to predict the performance of the ESP-ALI.



中文翻译:

粒子形态对用于纳米毒理学研究的静电气液界面细胞暴露系统性能的影响

摘要

颗粒形态会影响静电除尘器气液界面 (ESP-ALI) 细胞暴露系统的性能和由此产生的细胞毒性。在这项研究中,选择了三种类型的单分散气溶胶——球形蔗糖颗粒、非球形排列烟灰聚集体和纳米银聚集体/团聚体——以评估流速范围为 0.3 到 1.5 lpm 时的收集效率。为了量化颗粒形态,表征了测试气溶胶的分形维数 ( D f )。微粒(的渗透d p = 100-250不同的操作条件下纳米)使用无量纲漂移速度(一种特征指数曲线相关V Ç / Vavg,r ) 作为缩放参数。对于纳米颗粒(NP, d p <100纳米)具有不同的颗粒形态,在ESP-ALI粒子穿透相似,但它们的扩散损失不能忽略。相比之下,对于细颗粒,烟灰纳米聚集体 ( D f = 2.29)的收集效率高于球形蔗糖颗粒。这种差异可能是由于电场诱导和流场诱导对齐的同时影响。此外,基于志斌和国权的 Deutsch 模型,应用二次方程拟合实验数据并预测 ESP-ALI 的性能。

更新日期:2020-12-30
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