Age- and sex-specific reference intervals (RIs) for some biochemical tests may be useful for their interpretation, due to the variations in lifestyle and genetic, or ethnic factors. The aim of this study was to obtain RIs for some routine biochemical markers including a serum lipid profile, fasting blood glucose (FBG), aspartate and alanine aminotransferase (AST and ALT), uric acid, and body mass index (BMI) in subjects who attended primary healthcare centers. The large database of primary healthcare centers uses RIs to report results for children, adolescents, and young and old adults. RIs were obtained by using the indirect method, recommended by the CLSI Ep28-A3 guidelines. RIs for FBG, BMI, and serum lipid profile, including triglyceride, total cholesterol, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol in people aged 18 to 120 years, were obtained without age/sex segmentation. RIs for serum AST, ALT, and uric acid were obtained without age segmentation, though these RIs were higher in males than females. The RIs for AST, ALT, and uric acid were higher in men, while the RIs for the other variables were similar in both sexes. This is the first study reporting the use of indirect RIs for BMI.

中文翻译：

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常规生化指标和体重指数的参考区间：基于伊朗东北部医疗中心数据库的研究

由于生活方式和遗传或种族因素的差异，某些生化测试的年龄和性别特定参考区间 (RI) 可能有助于其解释。本研究的目的是获得一些常规生化标志物的 RI，包括血清脂质谱、空腹血糖 (FBG)、天冬氨酸和丙氨酸氨基转移酶 (AST 和 ALT)、尿酸和体重指数 (BMI)。参加初级保健中心。初级保健中心的大型数据库使用 RI 报告儿童、青少年和年轻人和老年人的结果。RI 是通过使用 CLSI Ep28-A3 指南推荐的间接方法获得的。用于 FBG、BMI 和血清脂质谱的 RI，包括甘油三酯、总胆固醇、高密度脂蛋白胆固醇、18 至 120 岁人群的低密度脂蛋白胆固醇和低密度脂蛋白胆固醇是在没有进行年龄/性别分割的情况下获得的。血清 AST、ALT 和尿酸的 RI 是在没有进行年龄分割的情况下获得的，尽管这些 RI 在男性中高于女性。男性的 AST、ALT 和尿酸的 RI 较高，而其他变量的 RI 在两性中相似。这是第一项报告将间接 RI 用于 BMI 的研究。