Recent advances focused on smart polymers have demonstrated the numerous advantages regarding other structures because they can adapt the behavior depending on physicochemical properties. In this way, functionalized thermoresponsive polymers with organometallic complexes were profoundly analyzed. Consequently, novel catalytic systems or biomedical devices could be developed. This publication focuses on the facile preparation of poly(N-isopropylacrylamide-co-dopamine methacrylamide) copolymers functionalized with triphenyltin chloride by protonolysis through the –OH of catechol groups. The presence of hydrophobic organotin(IV) derivatives could modify the solubility, thermoresponsive behavior, and other properties regarding pure copolymers. Also, sensitive analysis of the microstructure could help to understand the changes associated with the lower critical solution temperature by rheology, UV–vis spectroscopy, and calorimetry. In addition, a preliminary biological study against MDA-MB-231 cancer cells and peripheral blood mononuclear cells showed that the functionalized copolymers could be a potential platform to be explored in the future in the fight against cancer.

专注于智能聚合物的最新进展证明了关于其他结构的众多优势，因为它们可以根据物理化学性质来适应行为。以此方式，对具有有机金属配合物的官能化热响应性聚合物进行了深入分析。因此，可以开发新颖的催化系统或生物医学装置。该出版物集中在聚容易制备（Ñ -isopropylacrylamide-共-三巴胺氯化物通过邻苯二酚基团的-OH质子化作用而官能化的共聚物。疏水性有机锡（IV）衍生物的存在可能会改变溶解性，热响应行为以及有关纯共聚物的其他性能。同样，通过流变学，紫外可见光谱和量热法，对微观结构进行灵敏的分析可以帮助理解与较低的临界溶液温度相关的变化。此外，针对MDA-MB-231癌细胞和外周血单核细胞的初步生物学研究表明，功能化的共聚物可能会成为未来对抗癌症的潜在平台。