We report a facile and versatile approach to fabricate polyelectrolyte multilayer (PEM) films with a chemically modifiable outer surface. A PEM film was prepared by layer-by-layer assembly of poly (2-aminoethyl methacrylate) (PAMA) and polymethacrylic acid (PMAA), terminated with a partially tert-butyloxycarbonyl (Boc)-protected random copolymer (PAMA-co-PBocAMA) as the final layer. The obtained PEM film was then cross-linked and the free amino groups in the PEM film were quenched using EDC/NHS chemistry. The outer layer of the film was then treated via a deprotection reaction, affording free amino groups selectively located at the film surface. As a proof of concept study, these functional groups were used to modify the film surface with two model hydrophilic and hydrophobic compounds, which tuned the wettability of the PEM.

我们报告了一种简便且通用的方法来制造具有可化学修饰的外表面的聚电解质多层（PEM）膜。通过逐层组装聚（甲基丙烯酸2-氨基乙酯）（PAMA）和聚甲基丙烯酸（PMAA），并以部分由叔丁氧羰基（Boc）保护的无规共聚物（PAMA-co-PBocAMA）终止，制备PEM膜）作为最后一层。然后将获得的PEM膜交联，并使用EDC / NHS化学方法淬灭PEM膜中的游离氨基。然后通过脱保护反应处理膜的外层，得到选择性位于膜表面的游离氨基。作为概念研究的证明，这些官能团用于通过两种模型亲水和疏水化合物修饰膜表面，从而调节了PEM的润湿性。