Caryophyllales is one of the largest orders in eudicots and comprises 39 families with approximately 12,500 species. Although extracts from species of this order have been considered potential inhibitors of plant virus infection since the early 20th century, few species have actually been investigated. In this review, we present an exhaustive analysis of published papers that investigate this inhibitory effect, organized into one table with more than 100 species. In addition, the main hypotheses regarding the mode of action by which the compounds inhibit viral infection are discussed, providing several examples. The proteinaceous nature of antiviral proteins (AVP) produced by Caryophyllales, as well as the role of ribosome-inactivating proteins (RIPs) and pathogenesis-related proteins (PRs) as plant-defense inducers have received considerable attention. It is worth mentioning that data concerning the role of AVPs produced by species of Caryophyllales as signaling plant defense against viruses are scarce. Finally, this review proposes a model for the main mode of action hypotheses of viral infection inhibitors, and highlights the importance of surveying Caryophyllales species as an excellent strategy for controlling a broad spectrum of plant viruses from different taxonomic groups.

石竹叶肉是双子叶植物中最大的订单之一，由39个科组成，约有12,500种。尽管自20世纪初以来，该物种的提取物一直被认为是潜在的植物病毒感染抑制剂，但实际上尚未对任何物种进行过研究。在这篇综述中，我们对研究这种抑制作用的已发表论文进行了详尽的分析，并整理成一张表格，列出了100多种物种。此外，还讨论了有关化合物抑制病毒感染的作用方式的主要假设，并提供了一些实例。石竹叶肉产生的抗病毒蛋白（AVP）的蛋白质性质，以及核糖体失活蛋白（RIPs）和与病程相关的蛋白（PRs）作为植物防御诱导物的作用受到了广泛关注。值得一提的是，关于由石竹叶物种产生的AVP在信号传导植物防御病毒方面的作用的数据很少。最后，本综述提出了一种病毒感染抑制剂主要作用方式假说的模型，并强调了调查石竹叶物种作为控制不同分类组广泛植物病毒的出色策略的重要性。