Amongst heterocyclic compounds, quinoline is an advantaged scaffold that appears as a significant assembly motif for the development of new drug entities. Quinoline and its derivatives tested with diverse biological activity constitute an important class of compounds for new drug development. Therefore, many scientific communities have developed these compounds as intent structure and evaluated their biological activities. The present, review provides brief natural sources of quinoline and including a new extent of quinoline-based marketed drugs. This review also confers information about the biological activities of quinoline derivatives such as antibacterial, antifungal, antimycobacterial, antiviral, anti-protozoal, antimalarial, anticancer, cardiovascular, CNS effects, antioxidant, anticonvulsant, analgesic, anti-inflammatory, anthelmintic and miscellaneous activities.

在杂环化合物中，喹啉是一种有利的支架，作为开发新药实体的重要组装基序出现。经测试具有多种生物活性的喹啉及其衍生物构成了用于新药开发的一类重要化合物。因此，许多科学界已经开发了这些化合物作为意图结构并评估了它们的生物活性。目前，综述提供了喹啉的简要天然来源，包括新范围的喹啉上市药物。本综述还提供了有关喹啉衍生物生物活性的信息，例如抗菌、抗真菌、抗分枝杆菌、抗病毒、抗原生动物、抗疟、抗癌、心血管、中枢神经系统作用、抗氧化、抗惊厥、镇痛、抗炎、