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Decreased plasma rifapentine concentrations associated with AADAC single nucleotide polymorphism in adults with tuberculosis
Journal of Antimicrobial Chemotherapy ( IF 3.9 ) Pub Date : 2020-12-29 , DOI: 10.1093/jac/dkaa490 Marc Weiner 1, 2 , Jon Gelfond 1 , Teresa L Johnson-Pais 1 , Melissa Engle 1 , John L Johnson 3, 4 , William C Whitworth 5 , Erin Bliven-Sizemore 5 , Pheona Nsubuga 4 , Susan E Dorman 6 , Rada Savic 7 ,
Journal of Antimicrobial Chemotherapy ( IF 3.9 ) Pub Date : 2020-12-29 , DOI: 10.1093/jac/dkaa490 Marc Weiner 1, 2 , Jon Gelfond 1 , Teresa L Johnson-Pais 1 , Melissa Engle 1 , John L Johnson 3, 4 , William C Whitworth 5 , Erin Bliven-Sizemore 5 , Pheona Nsubuga 4 , Susan E Dorman 6 , Rada Savic 7 ,
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Rifapentine exposure is associated with bactericidal activity against Mycobacterium tuberculosis, but high interindividual variation in plasma concentrations is encountered.
中文翻译:
成人结核病患者中与 AADAC 单核苷酸多态性相关的血浆利福喷丁浓度降低
利福喷丁暴露与对结核分枝杆菌的杀菌活性有关,但血浆浓度的个体间差异很大。
更新日期:2020-12-30
中文翻译:
成人结核病患者中与 AADAC 单核苷酸多态性相关的血浆利福喷丁浓度降低
利福喷丁暴露与对结核分枝杆菌的杀菌活性有关,但血浆浓度的个体间差异很大。