Aniba rosaeodora is one of the most widely used plants in the perfumery industry, being used as medicinal plant in the Brazilian Amazon. This work aimed to evaluate the chemical composition of A. rosaeodora essential oil and its biological activities. A. rosaeodora essential oil presented linalool (93.60%) as its major compound. The A. rosaeodora essential oil and linalool showed activity against all the bacteria strains tested, standard strains and marine environment bacteria, with the lower minimum inhibitory concentration being observed for S. aureus. An efficient antioxidant activity of A. rosaeodora essential oil and linalool (EC₅₀: 15.46 and 6.78 µg/mL, respectively) was evidenced by the inhibition of the 2,2-azinobis- (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical. The antitrypanosomal activity of A. rosaeodora essential oil and linalool was observed at high concentrations against epimatigote forms (inhibitory concentration for 50% of parasites (IC₅₀): 150.5 ± 1.08 and 198.6 ± 1.12 µg/mL, respectively), and even higher against intracellular amastigotes of T. cruzi (IC₅₀: 911.6 ± 1.15 and 249.6 ± 1.18 µg/mL, respectively). Both A. rosaeodora essential oil and linalool did not exhibit a cytotoxic effect in BALB/c peritoneal macrophages, and both reduced nitrite levels in unstimulated cells revealing a potential effect in NO production. These data revealed the pharmacological potential of A. rosaeodora essential oil and linalool, encouraging further studies.

中文翻译：

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蔷薇（Vani。Amazonica Ducke）精油：化学成分，抗菌，抗氧化和抗胰锥Activity活性

玫瑰红（Aniba rosaeodora）是香水业中使用最广泛的植物之一，在巴西亚马逊河地区被用作药用植物。这项工作旨在评估玫瑰蔷薇精油的化学成分及其生物学活性。蔷薇A. rosaeodora精油以芳樟醇（93.60％）为主要成分。所述A. rosaeodora针对所有的细菌菌株进行测试，标准菌株和海洋环境中的细菌精油和芳樟醇显示活性，与所观察到的较低的最小抑制浓度的金黄色葡萄球菌。玫瑰蔷薇精油和芳樟醇的有效抗氧化活性（EC ₅₀：分别抑制了2,2-叠氮基双-（3-乙基苯并噻唑啉-6-磺酸）（ABTS）自由基，证明了：分别为15.46和6.78 µg / mL。观察到高浓度的玫瑰色A. rosaeodora精油和芳樟醇对表皮虫的抗胰蛋白酶活性（50％寄生虫的抑制浓度（IC ₅₀）分别为150.5±1.08和198.6±1.12 µg / mL），甚至更高。T. cruzi的胞内变形虫（IC ₅₀：分别为911.6±1.15和249.6±1.18 µg / mL）。这两个A. rosaeodora精油和芳樟醇在BALB / c腹膜巨噬细胞中未显示出细胞毒性作用，未​​刺激细胞中亚硝酸盐含量的降低都揭示了NO产生的潜在作用。这些数据揭示了玫瑰蔷薇精油和芳樟醇的药理潜力，这鼓励了进一步的研究。