The objective of this study was to identify predictive factors of mortality in older adults with coronavirus disease 2019 (COVID‐19), including the level of clinical frailty by using the clinical frailty scale (CFS). We analyzed medical records of all patients aged of 75 and older with a confirmed diagnosis of COVID‐19 hospitalized in our Hospital between March 3 and April 25, 2020. Standardized variables were prospectively collected, and standardized care were provided to all patients. One hundred and eighty‐six patients were included (mean 85.3 ± 5.78 year). The all cause 30‐day mortality was 30% (56/186). At admission, dead patients were more dyspneic (57% vs. 38%, p = .014), had more often an oxygen saturation less than 94% (70% vs. 47%, p < .01) and had more often a heart rate faster than 90/min (70% vs. 42%, p < .001). Mortality increased in parallel with CFS score (p = .051) (20 deaths (36%) in 7–9 category). In multivariate analysis, CFS score (odds ratio [OR] = 1.49; confidence interval [CI] 95%, 1.01–2.19; p = .046), age (OR = 1.15; CI 95%, 1.01–1.31; p = .034), and dyspnea (OR = 5.37; CI 95%, 1.33–21.68; p = .018) were associated with all‐cause 30‐day mortality. It is necessary to integrate the assessment of frailty to determine care management plan of older patients with COVID‐19, rather than the only restrictive criterion of age.

中文翻译：

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患有SARS-CoV-2感染的老年人：临床虚弱量表可用于预测死亡率

这项研究的目的是通过临床脆弱性量表（CFS）来确定2019年冠状病毒疾病老年人的死亡预测因素（COVID-19），包括临床脆弱性水平。我们分析了2020年3月3日至4月25日在我院住院的所有确诊为COVID-19的75岁及75岁以上患者的病历。前瞻性收集了标准化变量，并为所有患者提供了标准化护理。包括186例患者（平均85.3±5.78年）。30天全因死亡率为30％（56/186）。入院时，死亡患者的呼吸困难程度更高（57％比38％，p  = .014），氧饱和度通常低于94％（70％比47％，p）。 <.01），心率通常高于90 / min（70％vs. 42％，p  <.001）。死亡率与CFS评分同时升高（p  = .051）（7–9类中20例死亡（36％））。在多变量分析中，CFS评分（赔率[OR] = 1.49；置信区间[CI] 95％，1.01-2.19；p  = .046），年龄（OR = 1.15； CI 95％，1.01-1.13；p  =。 034）和呼吸困难（OR = 5.37； CI 95％，1.33–21.68；p  = .018 ）与全天30天死亡率相关。有必要整合脆弱性评估来确定COVID-19老年患者的护理管理计划，而不是唯一的年龄限制标准。