In Vitro Corrosion Resistance and Antibacterial Performance of Novel Fe–xCu Biomedical Alloys Prepared by Selective Laser Melting,Advanced Engineering Materials

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In Vitro Corrosion Resistance and Antibacterial Performance of Novel Fe–xCu Biomedical Alloys Prepared by Selective Laser Melting
Advanced Engineering Materials ( IF 3.4 ) Pub Date : 2020-12-30 , DOI: 10.1002/adem.202001000
Yingxue Guo ₁ , Ming-Chun Zhao ₁ , Bin Xie ₁ , Ying-Chao Zhao ₁ , Dengfeng Yin ₁ , Chengde Gao ₁ , Cijun Shuai ₁ , Andrej Atrens ₂

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Antibacterial Fe–xCu biomedical alloys are designed to have a satisfactory biodegradation rate compared with pure iron. Fe–xCu (x = 0, 1.5, 2.3, 7.8, and 10.1 wt%) alloys are produced by selective laser melting (SLM). Alloying with Cu has a signiﬁcant influence on the grain size, hardness, biodegradation rate, and antibacterial performance of SLMed Fe–xCu alloys. Increasing Cu content decreases the grain size and increases the hardness. SLMed Fe–1.5Cu, Fe–2.3Cu, and Fe–10.1Cu have degradation rates similar to that of pure iron, while the degradation rate of SLMed Fe–7.8Cu is almost 2.5 times faster. The SLMed Fe–2.3Cu, Fe–7.8Cu, and Fe–10.1Cu produce strong antibacterial performance. The mechanisms of degradation behavior and antibacterial performance are clarified. SLMed Fe–7.8Cu had appropriate mechanical properties, satisfactory degradation rates, strong antibacterial performance, and good cytocompatibility, and therefore is a novel type of antibacterial biomedical alloy with good potential for clinical application.

中文翻译：

选择性激光熔融制备的新型Fe–xCu生物医学合金的体外耐腐蚀性和抗菌性能

与纯铁相比，抗菌型Fe– x Cu生物医学合金具有令人满意的生物降解率。Fe– x Cu（x = 0、1.5、2.3、7.8和10.1 wt％）合金是通过选择性激光熔化（SLM）制成的。与Cu合金化对SLMed Fe– x的晶粒尺寸，硬度，生物降解速率和抗菌性能有重大影响铜合金。Cu含量的增加会减小晶粒尺寸并增加硬度。SLMed Fe–1.5Cu，Fe–2.3Cu和Fe–10.1Cu的降解速率与纯铁相似，而SLMed Fe–7.8Cu的降解速率几乎快2.5倍。SLMed Fe–2.3Cu，Fe–7.8Cu和Fe–10.1Cu具有很强的抗菌性能。阐明了降解行为和抗菌性能的机制。SLMed Fe–7.8Cu具有适当的机械性能，令人满意的降解速率，强大的抗菌性能和良好的细胞相容性，因此是一种新型的抗菌生物医学合金，具有良好的临床应用潜力。

更新日期：2020-12-30

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