There are two kinds of condensins in human cells, known as condensin I and condensin II. The canonical roles of condensins are participated in chromosome dynamics, including chromosome condensation and segregation during cell division. Recently, a novel function of human condensins has been found with increasing evidences that they play important roles in cellular senescence. This paper reviewed the research progress of human condensins involved in different types of cellular senescence, mainly oncogene-induced senescence (OIS) and replicative senescence (RS). The future perspectives of human condensins involved in cellular senescence are also discussed.

中文翻译：

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探索人类凝聚素在细胞衰老中的新功能

人细胞中有两种凝集素，称为凝集素I和凝集素II。凝集素的典型作用参与染色体动力学，包括细胞分裂过程中的染色体凝结和分离。近来，已发现人类凝缩蛋白的新功能，并且越来越多的证据表明它们在细胞衰老中起重要作用。本文综述了人类凝缩蛋白在不同类型细胞衰老中的研究进展，主要涉及致癌基因诱导衰老（OIS）和复制衰老（RS）。还讨论了人类凝缩蛋白参与细胞衰老的未来观点。