Background: Dysregulation of the inflammatory and immune response to injury may increase susceptibility to secondary infections after trauma. It is unknown whether cytokines involved in this response could function as plasma biomarkers for surgical site infection (SSI). We hypothesized that the early cytokine response differs between patients who develop SSI and those who do not and that critical cytokine threshold values could be used to predict risk of SSI.

中文翻译：

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早期单核细胞趋化蛋白 1 升高可预测钝性创伤后的手术部位感染

背景：对损伤的炎症和免疫反应失调可能会增加创伤后继发感染的易感性。目前尚不清楚参与这种反应的细胞因子是否可以作为手术部位感染 (SSI) 的血浆生物标志物。我们假设发生 SSI 的患者和未发生 SSI 的患者的早期细胞因子反应不同，并且关键的细胞因子阈值可用于预测 SSI 的风险。