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An open platform for high-resolution light-based control of microscopic collectives
bioRxiv - Synthetic Biology Pub Date : 2020-12-28 , DOI: 10.1101/2020.12.28.424547
Ana Rubio Denniss , Thomas E. Gorochowski , Sabine Hauert

Engineering microscopic collectives of cells or microrobots is challenging due to the often-limited capabilities of the individual agents, our inability to program their motion and local interactions, and difficulties visualising their behaviours. Here, we present a low-cost, modular and open-source Dynamic Optical MicroEnvironment (DOME) and demonstrate its ability to augment microagent capabilities and control collective behaviours using light. The DOME offers an accessible means to study complex multicellular phenomena and implement de-novo microswarms with desired functionalities.

中文翻译:

一个开放的平台,用于对微观集体进行高分辨率的基于光的控制

由于单个代理的能力通常有限,我们无法对它们的运动和局部相互作用进行编程以及难以可视化其行为,因此工程化细胞或微型机器人的微观集合体具有挑战性。在这里,我们提出了一种低成本,模块化和开放源代码的动态光学微环境(DOME),并展示了其增强微代理功能并使用光控制集体行为的能力。DOME提供了一种可访问的方法来研究复杂的多细胞现象并实现具有所需功能的新型微群。
更新日期:2020-12-29
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