Objective

To describe the effects of presurgical preparation with an isopropyl alcohol or water rinse on the perioperative rectal temperature (RT) of puppies and kittens.

Study design

Randomized clinical trial.

Animals

A total of 48 intact female mixed breed puppies and 43 intact female Domestic Short Hair kittens aged 8–18 weeks.

Methods

All animals were premedicated with intramuscular buprenorphine (0.02 mg kg^–1) and acepromazine (0.05 mg kg^–1). Anesthesia was induced with intravenous propofol (4 mg kg^–1 to effect) for puppies or ketamine (5 mg kg^–1) and midazolam (0.25 mg kg^–1) for kittens. RT was measured every minute for the first 15 minutes at the beginning of hair/fur removal, then every 5 minutes for 45 minutes (dogs) and 35 minutes (cats). All animals were prepared for surgery using a 1.6% chlorhexidine solution, then rinsed with either isopropyl alcohol (group CA) or water (group CW).

Results

Mean RT difference between the groups was not significant at any time point. The mean RT at 45 minutes for dogs was 35.9 °C and 36.0 °C in groups CA and CW, respectively (p = 0.74). The mean RT at 35 minutes for cats was 35.1 °C in both groups (p = 0.84).

Conclusions and clinical relevance

The use of either water or alcohol as a rinsing agent results in the same degree of perioperative temperature change. Other factors that contribute to perioperative hypothermia should be considered when choosing between these rinsing agents in surgical preparation of pediatric and small animals.

中文翻译：

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用异丙醇或水进行手术准备冲洗对儿科雌性犬猫围手术期体温的影响

客观的

描述使用异丙醇或水冲洗的术前准备对幼犬和小猫围手术期直肠温度 (RT) 的影响。

学习规划

随机临床试验。

动物

总共 48 只完整的雌性混合品种幼犬和 43 只完整的雌性家养短毛小猫 8-18 周龄。

方法

所有动物都预先用肌肉注射丁丙诺啡 (0.02 mg kg ^–1 ) 和乙酰丙嗪(0.05 mg kg ^–1 )。幼犬静脉注射丙泊酚（4 mg kg ^–1起效）诱导麻醉，小猫注射氯胺酮（5 mg kg ^–1）和咪达唑仑（0.25 mg kg ^–1）诱导麻醉。在开始去除毛发/皮毛的前 15 分钟，每分钟测量一次 RT，然后每 5 分钟测量一次，持续 45 分钟（狗）和 35 分钟（猫）。所有动物均使用 1.6% 氯己定溶液准备手术，然后用异丙醇（CA 组）或水（CW 组）冲洗。

结果

在任何时间点，组间的平均 RT 差异都不显着。在 CA 和 CW 组中，狗在 45 分钟时的平均 RT 分别为 35.9 °C 和 36.0 °C ( p  = 0.74)。两组猫在 35 分钟时的平均 RT 为 35.1 °C ( p  = 0.84)。

结论和临床相关性

使用水或酒精作为冲洗剂会导致围手术期温度变化程度相同。在儿科和小动物的手术准备中在这些冲洗剂之间进行选择时，应考虑导致围手术期体温过低的其他因素。