当前位置: X-MOL 学术Tetrahedron Lett. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Synthesis of 2-phosphonoheterocycles via base-promoted 5-endo cyclization
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2020-12-29 , DOI: 10.1016/j.tetlet.2020.152742
Ameni Bousbia , Mohamed Lamine Benkhoud , Laurent El-Kaïm , Sébastien Prévost

Herein, a synthesis of 2-phosphonodihydrofurans and 2-phosphonodihydropyrroles via 5-endo cyclization of O-and N-propargylated compounds is described. The reaction is promoted by potassium tert-butoxide and allows a fast access to interesting heterocycles which were easily converted into 2-arylated pyrroles under acidic conditions.



中文翻译:

通过碱促进的5-内环化反应合成2-膦杂环

此处,2- phosphonodihydrofurans和2- phosphonodihydropyrroles合成通过5-的O形环化Ñ -propargylated描述的化合物。该反应由丁醇钾促进,并允许快速进入有趣的杂环,这些杂环在酸性条件下容易转化为2-芳基吡咯。

更新日期:2021-01-21
down
wechat
bug