当前位置:
X-MOL 学术
›
Tetrahedron Lett.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
Synthesis of 2-phosphonoheterocycles via base-promoted 5-endo cyclization
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2020-12-29 , DOI: 10.1016/j.tetlet.2020.152742 Ameni Bousbia , Mohamed Lamine Benkhoud , Laurent El-Kaïm , Sébastien Prévost
中文翻译:
通过碱促进的5-内环化反应合成2-膦杂环
更新日期:2021-01-21
Tetrahedron Letters ( IF 1.5 ) Pub Date : 2020-12-29 , DOI: 10.1016/j.tetlet.2020.152742 Ameni Bousbia , Mohamed Lamine Benkhoud , Laurent El-Kaïm , Sébastien Prévost
Herein, a synthesis of 2-phosphonodihydrofurans and 2-phosphonodihydropyrroles via 5-endo cyclization of O-and N-propargylated compounds is described. The reaction is promoted by potassium tert-butoxide and allows a fast access to interesting heterocycles which were easily converted into 2-arylated pyrroles under acidic conditions.
中文翻译:
通过碱促进的5-内环化反应合成2-膦杂环
此处,2- phosphonodihydrofurans和2- phosphonodihydropyrroles合成通过5-内的O形环化Ñ -propargylated描述的化合物。该反应由叔丁醇钾促进,并允许快速进入有趣的杂环,这些杂环在酸性条件下容易转化为2-芳基吡咯。