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Ethnopharmacological study of herbal remedies used for the management of thyroid disorders in Algeria
Saudi Pharmaceutical Journal ( IF 3.0 ) Pub Date : 2020-12-29 , DOI: 10.1016/j.jsps.2020.12.004
Khaled Taïbi 1 , Leila Ait Abderrahim 1 , Fatima Helal 1 , Khalida Hadji 1
Affiliation  

Traditional medicine is gaining an increasing importance in diseases management. Besides, thyroid disease is one of the common endocrine disorders spreading at high frequency worldwide. The present work is an ethnopharmacological study aiming to identify, document and analyze aromatic and medicinal plants used in Algerian traditional medicines for thyroid disorders management. Semi-structured interviews with 120 herbalists and traditional practitioners and rural dwellers were realized in eleven locations in Algeria throughout field studies achieved from June 2017 to July 2019. Results reveal the use of 63 medicinal plants belonging to 59 genera and 34 families. The most represented botanical families were Lamiaceae, Fabaceae, Apiaceae, Amaranthaceae and Asteraceae. However, the most cited plant species were Atriplex halimus L., Bunium incrassatum (Boiss.) Amo, Nigella sativa L., Aquilaria malaccensis Lam. and Saussurea costus (Falc.) Lipsch. These species are taken alone or in mixtures of two or more ingredients from different origins such as honey, olive oil, and goat milk. Our findings revealed new therapeutic uses of 60 medicinal plants that have not been previously reported for the treatment of thyroid in Algeria. This is the first study documenting the traditional uses based on herbal medicine for thyroid management in Algeria. Our findings are relevant in the search for novel drug discovery. Obviously, it is the time to increase effective scientific studies on mechanisms of action of these medicinal plants in order to validate their popular usages.



中文翻译:


阿尔及利亚用于治疗甲状腺疾病的草药的民族药理学研究



传统医学在疾病管理中变得越来越重要。此外,甲状腺疾病是全球范围内高发的常见内分泌疾病之一。目前的工作是一项民族药理学研究,旨在识别、记录和分析阿尔及利亚治疗甲状腺疾病的传统药物中使用的芳香和药用植物。在 2017 年 6 月至 2019 年 7 月期间进行的实地研究中,我们在阿尔及利亚的 11 个地点对 120 名草药师、传统从业者和农村居民进行了半结构化访谈。结果显示了属于 34 个科 59 属的 63 种药用植物的用途。最有代表性的植物科是唇形科、豆科、伞形科、苋科和菊科。然而,引用最多的植物物种是滨藜(Atriplex halimus L.)、 Bunium incrassatum (Boiss.) Amo、 Nigella sativa L.、 Aquilaria malaccensis Lam。和雪莲(Falc.) Lipsch。这些物种可以单独服用,也可以混合两种或多种来自不同来源的成分(例如蜂蜜、橄榄油和羊奶)服用。我们的研究结果揭示了 60 种药用植物的新治疗用途,这些植物此前在阿尔及利亚治疗甲状腺方面尚未有报道。这是第一项记录阿尔及利亚基于草药的传统用途用于甲状腺管理的研究。我们的发现与寻找新药发现相关。显然,现在是时候加强对这些药用植物作用机制的有效科学研究,以验证它们的普遍用途了。

更新日期:2021-02-03
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