The intake of antinutritional factors produce impairment on the intestinal digestive function, impeding the efficient use of nutrients. Probiotics could be useful in poultry breeding to prevent negative effects of antinutritional factors, like the dietary lectins soybean agglutinin (SBA) and wheat germ agglutinin (WGA). Therefore, this investigation aimed to verify that SBA and wheat, which contains WGA, exert harmful effects on the intestinal mucosa and the digestive system of young poultry, and determine if the administration of probiotics able to capture lectins could counteract their effects. The trials performed demonstrated that a mixture of Bifidobacterium infantis CRL 1395, Enterococcus faecium LET 301, Lactobacillus salivarius LET 201, L. reuteri LET 210, and Propionibacterium acidipropionici LET 103, strains with ex vivo ability to interfere with the interaction of lectins and epithelial cells, has no negative effect on young chickens health. Middle levels of SBA, as well as wheat as a source of WGA, resulted in lower activities of intestinal and brush border enzymes and alterations in the integrity and morphological parameters of the chicks jejunal mucosa. The bacteria blend increased the activity of several digestive enzymes and the intestinal maturation marker alkaline phosphatase in birds fed with a conventional diet. Besides, it partially countered the deleterious effects of increased content of SBA, as well as the negative effect of a dietary source of WGA, on digestive enzymes activity and intestinal mucosa integrity. The results highlight the capability of multifunctional bacterial mixtures to protect the digestive system of avian against residual dietary lectins.

摄入抗营养因子会损害肠道的消化功能，从而阻碍营养物质的有效利用。益生菌可用于家禽育种中，以防止抗营养因子（如膳食凝集素，大豆凝集素（SBA）和小麦胚芽凝集素（WGA））的负面影响。因此，本研究旨在验证含有WGA的SBA和小麦对肠道粘膜和年轻家禽的消化系统产生有害影响，并确定施用能够捕获凝集素的益生菌是否可以抵消其影响。进行的试验表明，婴儿双歧杆菌CRL 1395，粪肠球菌LET 301，唾液乳杆菌LET 201，罗伊氏乳杆菌LET 210，和丙酸产丙酸丙酸杆菌LET 103，与菌株离体干扰凝集素和上皮细胞相互作用的能力，对雏鸡的健康没有负面影响。SBA的中等水平以及小麦作为WGA的来源，导致肠道和刷缘酶的活性降低，雏鸡空肠黏膜的完整性和形态学参数发生变化。这种细菌混合物增加了用常规饮食喂养的禽类中几种消化酶和肠成熟标记物碱性磷酸酶的活性。此外，它部分抵消了SBA含量增加的有害作用以及WGA饮食来源对消化酶活性和肠粘膜完整性的不利影响。