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Mild cognitive impairment is associated with fall-related injury among adults aged ≥65 years in low- and middle-income countries
Experimental Gerontology ( IF 3.3 ) Pub Date : 2020-12-29 , DOI: 10.1016/j.exger.2020.111222
Lee Smith , Louis Jacob , Karel Kostev , Laurie Butler , Yvonne Barnett , Briona Pfeifer , Pinar Soysal , Igor Grabovac , Guillermo F. López-Sánchez , Nicola Veronese , Lin Yang , Hans Oh , Ai Koyanagi

Objectives

There is a scarcity of data on the association between mild cognitive impairment (MCI) and falls, especially from low- and middle-income countries (LMICs) where 70% of all older adults reside. Thus, we investigated the association between MCI and fall-related injury among older adults residing in six LMICs (China, Ghana, India, Mexico, Russia, South Africa).

Design

Cross-sectional, community-based data from the WHO Study on global AGEing and adult health (SAGE) were analyzed.

Methods

The definition of MCI was based on the National Institute on Ageing-Alzheimer's Association criteria, and information on past 12-month fall-related injury was also collected. Multivariable logistic regression analysis was conducted to assess associations.

Results

The analytical sample consisted of 13,623 individuals aged ≥65 years [mean (SD) age 72.3 (10.9) years; 45.6% males]. The prevalence of fall-related injury was higher among those with MCI (6.3%) vs. no MCI (4.1%). After adjustment for potential confounders, MCI was associated with a 1.53 (95%CI = 1.12–2.07) times higher odds for fall-related injury.

Conclusions

MCI was associated with higher odds for fall-related injury among older adults in LMICs. Future studies are warranted to investigate the mechanisms underlying this association and to elucidate whether targeting those with MCI can lead to reduced risk for falls among older adults.

更新日期:2021-01-04
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