A new neo-lignan, (7′S,8′R)-4′,5′,9′-trihydroxy-4,6-dimethoxy-5,8′-oxyneolign-7-en-9-al (1), along with 5 known compounds (2-6), were isolated from the fruits of Xanthium strumarium. Their structures were elucidated by extensive spectroscopic methods. All the isolates were evaluated for in vitro cytotoxicities against the human cancer lines HepG2, A549, HCT-116, and SGC-7901. Compounds 1 and 3 showed potent antiproliferative effects against A549 cancer cells with half-maximal inhibitory concentration (IC₅₀) values of 11.2 and 8.3 µM, respectively. In addition, compound 3 exhibited moderate cytotoxicity to SGC-7901 cancer cells, with an IC₅₀ value of 12.9 µM.

一种新的新木脂素，（7'小号，8 'R）-4'，5'，9'-三羟基-4,6-二甲氧基- 5,8'-oxyneolign -7-烯-9-人（1） ，用5种已知化合物（沿2 - 6），从果实中分离苍耳。通过广泛的光谱方法阐明了它们的结构。评估了所有分离株对人癌症细胞HepG2，A549，HCT-116和SGC-7901的体外细胞毒性。化合物1和3对A549癌细胞具有有效的抗增殖作用，其最大抑制浓度（IC ₅₀）值的一半分别为11.2和8.3 µM。另外，化合物3对SGC-7901癌细胞具有中等的细胞毒性，IC ₅₀值为12.9 µM。