Literary-rhetorical devices like figurative language and analogy can help explain concepts that exceed our capacity to grasp intuitively. It is not surprising these devices are used to discuss virulence, pathogenesis, and antibiotics. Allusions to Robert Louis Stevenson’s Strange Case of Dr. Jekyll and Mr. Hyde seem to be used with particular frequency in research pertaining to pathogens, especially in studies contemporary with our evolving understanding of antibiotic resistance. More recent references to the text have appeared in research parsing definitions of virulence and acknowledging the role of anti-virulence in future therapeutics. While it is obvious that scientists invoke Stevenson’s story for stylistic purposes, its use could go beyond the stylistic—and might even generate rhetorical and imaginative possibilities for framing research. This perspective discusses the first published allusion to Jekyll and Hyde in reference to virulence and pathogenesis; comments on a select number of specific instances of Jekyll and Hyde in contemporary scientific literature; briefly contextualizes the novel; and concludes with the implications of a more productive engagement with humanistic disciplines in the face of antibiotic resistance.

中文翻译：

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Jekyll博士和Hyde先生在抗生素研究中的案例并不那么奇怪：跨学科的机会

比喻语言和类比等文学修辞工具可以帮助解释超出我们直观理解能力的概念。这些设备用于讨论毒力，发病机理和抗生素也就不足为奇了。罗伯特·路易斯·史蒂文森（Robert Louis Stevenson）的杰基尔博士（Jekyll）和海德（Hyde）先生的奇怪案子的典故似乎在与病原体有关的研究中使用频率特别高，尤其是在我们对抗生素抗性的了解不断发展的当代研究中。在解析毒力定义并认识到抗毒力在未来治疗方法中的作用的研究中，出现了更多有关本文的参考。虽然很明显，科学家出于风格目的调用史蒂文森的故事，但它的用途可能超出了风格，甚至可能为构架研究带来修辞和想象力。这种观点讨论了关于毒力和发病机理的第一个发表给杰基尔和海德的典故。对选定的Jekyll和Hyde特定实例的评论在当代科学文献中；简要介绍小说的背景；并得出结论，面对抗生素抗药性，与人文学科进行更有成效的互动所带来的影响。