Relationships between retinal layer thickness and brain volumes in the UK Biobank cohort,European Journal of Neurology

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Relationships between retinal layer thickness and brain volumes in the UK Biobank cohort
European Journal of Neurology ( IF 4.5 ) Pub Date : 2020-12-28 , DOI: 10.1111/ene.14706
Sharon Y L Chua ₁ , Gerassimos Lascaratos _{2,

3} , Denize Atan _{4,

5} , Bing Zhang ₆ , Charles Reisman ₇ , Peng T Khaw ₁ , Stephen M Smith ₈ , Paul M Matthews ₉ , Axel Petzold ₁ , Nicholas G Strouthidis ₁ , Paul J Foster ₁ , Anthony P Khawaja ₁ , Praveen J Patel ₁ ,

Affiliation

Current methods to diagnose neurodegenerative diseases are costly and invasive. Retinal neuroanatomy may be a biomarker for more neurodegenerative processes and can be quantified in vivo using optical coherence tomography (OCT), which is inexpensive and noninvasive. We examined the association of neuroretinal morphology with brain MRI image‐derived phenotypes (IDPs) in a large cohort of healthy older people.

中文翻译：

英国生物银行队列中视网膜层厚度与脑容量之间的关系

目前诊断神经退行性疾病的方法成本高昂且具有侵入性。视网膜神经解剖学可能是更多神经退行性过程的生物标志物，并且可以使用光学相干断层扫描 (OCT) 在体内进行量化，这是一种廉价且无创的方法。我们在一大群健康老年人中检查了神经视网膜形态与大脑 MRI 图像衍生表型 (IDP) 的关联。

更新日期：2020-12-28

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