As managers and decision makers evaluate pollutant risk, it is critical that we are able to measure an assessment of the injury. Often, these estimates are difficult to determine for benthic organisms, so in 2017 a chronic polychlorinated biphenyl (PCB) sediment dose–response model to predict benthic invertebrate injury was proposed. Given both natural resource trustee and consultant questions following publication concerning that the aqueous chronic toxicity testing data used in the 2017 model development were primarily from the 1970s and 1980s, this follow‐up short communication is meant to provide the user some additional data that are more recent. With the advances in analytical and quantitative environmental chemistry (i.e., better detection limits and congener separation), we chose to complete acute aquatic toxicity testing using 3 estuarine invertebrates and lethal endpoints (20 and 50% lethal concentrations). This acute testing was selected because chronic aquatic testing for PCBs outside of the data used in the 2017 study was not available to us. The aquatic results used in the present study were changed to sediment using equilibrium partitioning, as done in the 2017 chronic model, after using the same organic–carbon partition coefficient and total organic carbon for our equilibrium partitioning (EqP)–measured calculations. Based on these acute aquatic toxicity results and a general acute‐to‐chronic injury concentration ratio of approximately 10, we found that the 2017 model was valid and, hence, that a 1.0 µg/g chronic PCB sediment criterion is a reasonable estimation of potential benthic invertebrate injury. This was followed by spiked sediment tests where percent acute sediment injury was compared to the EqP‐derived chronic value and the results from 2017; modest agreement is shown. Environ Toxicol Chem 2021;40:1188–1193. Published 2020. This article is a U.S. Government work and is in the public domain in the USA.

中文翻译：

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支持 2017 年慢性剂量反应沉积物损伤模型的急性多氯联苯底栖无脊椎动物毒性测试

当管理人员和决策者评估污染物风险时，我们能够衡量伤害评估是至关重要的。通常，这些估计对于底栖生物很难确定，因此在 2017 年提出了一个慢性多氯联苯 (PCB) 沉积物剂量反应模型来预测底栖无脊椎动物损伤。考虑到自然资源受托人和顾问在发布后提出的问题，即 2017 年模型开发中使用的水性慢性毒性测试数据主要来自 1970 年代和 1980 年代，此后续简短交流旨在为用户提供一些额外的数据，这些数据更最近的。随着分析和定量环境化学的进步（即更好的检测限和同系物分离），我们选择使用 3 种河口无脊椎动物和致死终点（20% 和 50% 致死浓度）完成急性水生毒性测试。之所以选择这种急性测试，是因为我们无法获得 2017 年研究中使用的数据之外的多氯联苯慢性水生测试。在使用相同的有机碳分配系数和总有机碳进行平衡分配 (EqP) 测量计算后，本研究中使用的水生结果更改为使用平衡分配的沉积物，如 2017 年慢性模型中所做的那样。基于这些急性水生毒性结果和大约 10 的一般急性慢性损伤浓度比，我们发现 2017 年模型是有效的，因此，1.0 µg/g 慢性多氯联苯沉积物标准是潜在的合理估计底栖无脊椎动物损伤。-衍生的慢性值和 2017 年的结果；显示了适度的协议。环境毒理学化学2021；40：1188-1193。2020 年出版。本文为美国政府作品，在美国属于公有领域。