Nicotiana glauca belonging to the family Solanaceae is an exotic perinnial bushy species that recently has invaded the mountainous areas of Al-Baha region at the south-west of Saudi Arabia, causing degredation to soil and vegetation composition of those mountains. Accordingly, this plant must be either removed or exploited as a source of useful products such as medicines as it has been proven to contain many effective compounds with therapeutic properties. Thus, the current study aimd to screening N. glauca preliminary phytoconsitiuents and its anticmicrobial activity. Results showed that varying amounts of alkaloids, steroid, tannins, flavonoid, were present in the extracts of N. glauca leaves, stems and flowers. Saponins were present only in the flowers extract. However, all previuos bioactive compounds were absent in the roots except alkaloids, therefore, roots posses lesser amount of the phytoconstituents compared to the other parts of the plants. Leaves extracts inhibited the growth of E. coli (16.3 ± 0.71 mm) and also inhibited the growth of S. aureus (11.0 ± 0.23 mm), while, the flower extracts also inhibited the growth of E. coli (6.7 ± 0.65 mm), and also inhibited the growth of S. aureus (15.8 ± 0.52 mm). This result coincide with the previous results of the screening of N, glauca phytochemicals where the highest amounts found in leaves and flowers extracts. The inhibition zone of the antibiotic gentamycin (reference control) were 32 mm in S. aureus and 38 mm in E. coli. The inhibition zone of gentamycin (reference control) were 32 mm in S. aureus and 38 mm in E. coli. The minimum inhibitory concentration (MIC) of ethyl acetate was ranged (1.5–2 mg/ml). The lower MIC is an indication of high effectiveness of extract. Therefore, such bioactive property would support the idea that removing N. glauca from the mountainous areas of Al-Baha, Saudi Arabia, is not the only solution, but the plant can be exploited as a beneficial source of medicinal and economic purposes such as; antibacterial, antifungal and insecticidal, however, further comprehensive exploration is recommended to confirm such propreties.

茄科的烟草（Nicotiana glauca）是一种外来的灌木丛生物种，最近入侵了沙特阿拉伯西南部的Al-Baha地区的山区，导致这些山区的土壤和植被组成退化。因此，由于已经证明该植物含有许多具有治疗特性的有效化合物，因此必须将该植物移走或用作有用产品（例如药物）的来源。因此，当前的研究旨在筛选青枯奈瑟氏菌初步植物组成及其抗微生物活性。结果表明，青草叶，茎和花的提取物中存在不同数量的生物碱，类固醇，单宁，类黄酮。皂苷仅存在于花朵提取物中。但是，除生物碱外，所有以前的生物活性化合物都不存在于根中，因此，与植物的其他部分相比，根具有较少的植物成分。叶提取物抑制大肠杆菌的生长（16.3±0.71 mm），也抑制金黄色葡萄球菌（11.0±0.23 mm）的生长，而花提取物也抑制大肠杆菌的生长（6.7±0.65 mm） ，并且也抑制了金黄色葡萄球菌（15.8±0.52 mm）的生长。该结果与先前筛选的N，青冈植物化学物质的结果一致，其中叶和花提取物中的含量最高。抗生素庆大霉素（参考对照）的抑制区在金黄色葡萄球菌中为32 mm，在大肠杆菌中为38 mm。庆大霉素（参考对照）的抑制区在金黄色葡萄球菌中为32 mm，在大肠杆菌中为38 mm。乙酸乙酯的最小抑菌浓度（MIC）为（1.5–2 mg / ml）。MIC较低表明提取物具有很高的功效。因此，这种生物活性特性将支持以下观点：从沙特阿拉伯的Al-Baha山区去除蓝叶猪笼草不是唯一的解决方案，但该植物可被用作医学和经济目的的有益来源，例如；抗菌，抗真菌和杀虫剂，但是，建议进一步综合探索以确认这种性质。