This highlight summarizes a recent development of a catalytic enantioselective Catellani-type reaction for the synthesis of axially chiral biaryls. The chirality induction is solely governed by chiral norbornene ligand in the Pd mediated ortho C¨CH functionalization and ipso cross-coupling transformation. The preparative power of the methodology is demonstrated as a powerful manifold for the divergent synthesis of structurally diverse axially chiral biaryls and chiral fluorenols.

中文翻译：

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催化不对称Catellani型反应：轴向手性构建的强大工具

该亮点总结了用于合成轴向手性联芳基的催化对映选择性卡塞拉尼型反应的最新进展。手性诱导仅受Pd介导的邻位C-CH功能化和ipso交叉偶联转化中的手性降冰片烯配体控制。该方法的制备能力被证明是结构多样的轴向手性联芳基和手性芴醇的不同合成的强大流形。