Endoxifen: A new, protein kinase C inhibitor to treat acute and mixed mania associated with bipolar I disorder,Bipolar Disorders

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Endoxifen: A new, protein kinase C inhibitor to treat acute and mixed mania associated with bipolar I disorder
Bipolar Disorders ( IF 5.0 ) Pub Date : 2020-12-25 , DOI: 10.1111/bdi.13041
Ateeq Ahmad ₁ , Saifuddin Sheikh ₁ , Mujtaba Ali Khan ₂ , Alok Chaturvedi ₂ , Piyush Patel ₂ , Ronak Patel ₃ , Bakul Chandrakant Buch ₄ , Rajendra Someshwar Anand ₅ , Timirkumar Chandrakant Shah ₆ , Vaishal Nareshchandra Vora ₇ , Vikhram Ramasubramanian ₈ , Satyanarayana Rao ₉ , Narendra Kumar ₁₀ , B S V Prasad ₁₁ , Ramanathan Sathianathan ₁₂ , Kamal Kumar Verma ₁₃ , Venu Gopal Jhanwar ₁₄ , Nand Kumar ₁₅ , Sandip Shah ₁₆ , Pronob Kumar Dalal ₁₇ , Brahmdeep Sindhu ₁₈ , Payel Talukdar ₁₉ , Imran Ahmad ₁

Affiliation

Jina Pharmaceuticals Inc, Libertyville, IL, USA.
Intas Pharmaceuticals Ltd, Ahmedabad, Gujarat, India.
Lambda Therapeutic Research Ltd, Ahmedabad, Gujarat, India.
Shri Hatkesh Healthcare Foundation, Junagadh, Gujarat, India.
Kanoria Hospital and Research Centre, Gandhinagar, Gujarat, India.
Divyam Hospital, Surat, Gujarat, India.
Ratandeep Multispecialty Hospital, Ahmedabad, Gujarat, India.
Ahana Hospitals, Madurai, Tamil Nadu, India.
JSS Medical College Hospital, Mysore, Karnataka, India.
Mysore Medical College and Research Institute, K.R. Hospital, Mysore, Karnataka, India.
Sujata Birla Hospital and Medical Research Center, Nasik, Maharashtra, India.
Sri Ramachandra Medical College and Research Institute, Chennai Tamil Nadu, India.
S.P. Medical College and A.G. Hospitals, Bikaner, Rajasthan, India.
Deva Institute of Healthcare and Research, Varanasi, Uttar Pradesh, India.
All India Institute of Medical Sciences, New Delhi, India.
Gujarat Medical Education & Research Society Medical College, Gotri, Vadodara, India.
King George's Medical University, G.M. Associated Hospitals, Lucknow, Uttar Pradesh, India.
Civil Hospital, Gurugram, Haryana, India.
Nil Ratan Sircar Medical College and Hospital, Kolkata, West Bengal, India.

Endoxifen is a protein kinase C inhibitor. The objective of the present phase III study was to demonstrate the safety and efficacy of endoxifen in treating bipolar I disorder (BPD I) patients.

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