Anti-cancer therapeutics of the highest calibre currently focus on combinatorial targeting of specific oncoproteins and tumour suppressors. Clinical relapse depends upon intratumoral heterogeneity which serves as substrate variation during evolution of resistance to therapeutic regimens.

中文翻译：

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单细胞系统分析：异常值中的决策几何

目前，最高水准的抗癌疗法专注于特定癌蛋白和肿瘤抑制因子的组合靶向。临床复发取决于肿瘤内异质性，肿瘤内异质性作为治疗方案耐药性演变过程中的底物变异。