Abstract

In this study, the essential oil composition and antibacterial activity of the resin of Canarium strictum Roxb. was investigated. The oil was extracted by microwave-assisted extraction and analyzed through gas chromatography-mass spectrometry by means of which 35 compounds were successfully identified. A substantial yield of essential oil (1.10%) was obtained from the resin. The most abundant ingredients were (R)-(+)-limonene (59.03%) and 1 R-(+)-α-pinene (24.06%). Antibacterial activity evaluation was performed against five bacterial strains four of which were multidrug-resistant. The oil was found to be active against all the strains. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values in mg/mL were calculated where MIC values were: methicillin-resistant Staphylococcus aureus (>0.66), Pseudomonas aeruginosa (1.33), Klebsiella pneumoniae (5.3), resistant Escherichia coli (>0.66) and non-resistant Escherichia coli (5.3).

摘要

在这项研究中， Canarium strictum Roxb树脂的精油成分和抗菌活性。进行了调查。采用微波辅助萃取法提取油，并通过气相色谱-质谱法分析，成功鉴定出 35 种化合物。从树脂中获得大量的精油（1.10%）。最丰富的成分是 (R)-(+)-柠檬烯 (59.03%) 和 1 R-(+)-α-蒎烯 (24.06%)。对五种细菌菌株进行了抗菌活性评估，其中四种菌株具有多重耐药性。发现这种油对所有菌株都有活性。计算以 mg/mL 为单位的最低抑菌浓度 (MIC) 和最低杀菌浓度 (MBC) 值，其中 MIC 值为：耐甲氧西林金黄色葡萄球菌(>0.66)、铜绿假单胞菌(1.33)、肺炎克雷伯菌(5.3)、耐药大肠杆菌(>0.66) 和非耐药大肠杆菌(5.3)。