Flow cytometry immunophenotyping (FCIP) can improve diagnosis of myelodysplastic syndromes (MDS) and myelodysplastic/myeloproliferative neoplasms (MDS/MPN), although its application is challenging due to difficulties in standardization, complexity of antibody panels and subjective interpretation of data. Since blasts are invariably affected in these disorders, we developed a FCIP approach for detailed and objective analysis of the blast population.

中文翻译：

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探索骨髓增生异常综合征和骨髓增生异常/骨髓增生性肿瘤中的原始细胞成分：CD45RA 和 CD371 通过评估成髓细胞异质性和干细胞异常提高流式细胞术的诊断价值

流式细胞术免疫表型 (FCIP) 可以改善骨髓增生异常综合征 (MDS) 和骨髓增生异常/骨髓增生性肿瘤 (MDS/MPN) 的诊断，尽管由于标准化困难、抗体组合的复杂性和数据的主观解释，其应用具有挑战性。由于爆炸总是受到这些疾病的影响，我们开发了一种 FCIP 方法，用于对爆炸人群进行详细和客观的分析。