The biocatalytic oxidation exists widely in biochemical industry. However, the oxidation reaction rate is usually limited by oxygen mass transfer. In this work, an inner-loop rotor-stator reactor (IL-RSR) was employed as a promising reactor for the process intensification of oxygen mass transfer, aiming to match the rate of oxidation reaction. The oxygen mass transfer coefficient (k_La) of the IL-RSR was experimentally studied. Then, the biocatalytic oxidation of glucose to produce sodium gluconate (SG) was selected as an example of working system to evaluate biocatalytic oxidation performance of the IL-RSR. The results indicated that the experimental value of k_La was in the range of 0.00984∼0.02758 s⁻¹ in the IL-RSR. The SG production rate was up to 6∼12 g/(L·h) in the IL-RSR, which was 7 times that in a stirred tank reactor (STR). IL-RSR shows potential prospects in the field of biocatalytic oxidations.

生物催化氧化在生化工业中广泛存在。但是，氧化反应速率通常受氧传质的限制。在这项工作中，内环转子-定子反应器（IL-RSR）被用作有前途的反应器，以增强氧气的传质过程，以匹配氧化反应的速度。实验研究了IL-RSR的氧传质系数（k _L a）。然后，以葡萄糖的生物催化氧化生成葡萄糖酸钠（SG）为例，作为评估IL-RSR的生物催化氧化性能的工作系统实例。结果表明，k _L a的实验值在0.00984〜0.02758 s ^-1范围内。在IL-RSR中。在IL-RSR中，SG的生产率高达6〜12g /（L·h），是搅拌釜反应器（STR）的7倍。IL-RSR在生物催化氧化领域显示出潜在的前景。