The Co(II) complex based on 2-propyl-1H-imidazole-4,5-dicarboxy acid (H2L) is synthesized and characterized. The interaction between the Co complex and fish sperm DNA(FS–DNA) are studied by fluorescence. The flow cytometry analysis shows that the Co complex can induce the apoptosis of HeLa (human cervix epithelia carcinoma cells) tumor cell lines. According to the fluorescence and apoptosis effects, it is speculated that the compound has a potential application value in the field of anticancer agents, and its properties need to be further explored.

中文翻译：

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由 2-PROPYL-1H-咪唑-4,5-二羧酸构成的 Co (II) 络合物的合成、表征、DNA 结合和抗癌能力

合成并表征了基于 2-丙基-1H-咪唑-4,5-二羧酸 (H2L) 的 Co (II) 配合物。通过荧光研究 Co 复合物和鱼精子 DNA (FS-DNA) 之间的相互作用。流式细胞术分析表明，Co复合物可诱导HeLa（人宫颈上皮癌细胞）肿瘤细胞系凋亡。根据荧光和凋亡效应推测该化合物在抗癌药物领域具有潜在的应用价值，其性质有待进一步探索。