Mushrooms are rich in ergosterol, a precursor of ergocalciferol, which is a type of vitamin D₂. The conversion of ergosterol to ergocalciferol takes place in the presence of UV radiation by the cleavage of the “B-ring” in the ergosterol. As the UV radiation cannot penetrate deep into the tissue, only minimal increase occurs in sunlight. In this study, upconversion nanoparticles with the property to convert deep-penetrating near-infrared radiation to UV radiation have been cast into a disk to use sunlight and emit UV radiation for vitamin D conversion. An engineered upconversion nanoparticle (UCNP) disk with maximum particles and limited clusters demonstrates ∼2.5 times enhanced vitamin D₂ conversion.

中文翻译：

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上转换纳米器件辅助的健康分子光校正

蘑菇富含麦角固醇（麦角钙化固醇的前体），麦角固醇是一种维生素D ₂。麦角固醇向麦角钙化固醇的转化在紫外线辐射的存在下通过麦角固醇中“ B环”的裂解而发生。由于紫外线辐射无法穿透到组织的深处，因此在阳光下只会出现极少的增加。在这项研究中，具有将深穿透的近红外辐射转换为UV辐射的特性的上转换纳米颗粒已被铸造到磁盘中，以利用太阳光并发射UV辐射进行维生素D转化。工程化的上转换纳米粒子（UCNP）圆片具有最大的粒子数和有限的簇，显示维生素D ₂转化率提高了约2.5倍。