ABSTRACT

Iron oxide nanoparticles (IONPs) were synthesised by combining the extracts of new plants (trigonella and tomato) with ferric chloride salt (FeCl₃) via a simple chemical method at 200°C for 2 hours. The biomolecules in the extracts play an important part in transforming FeCl₃ to FeO NPs, which demonstrate antibacterial properties. IONPs were characterised via X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), and Fourier-transform infrared spectroscopy (FT-IR). XRD revealed a crystallite size of 17 nm with a body centre cubic (BCC) structure (wüstite) phase for FeO NPs made using trigonella extract. FeO NPs synthesised using tomato extract were 41 nm, and the diffraction peaks revealed a BCC structure phase with excellent crystal quality. FE-SEM images demonstrated that the average grain size of Fe₂O₃ without using any plant extract was approximately 31.36 to 125.5 nm, while for the FeO NPs using tomato extract, it was approximately 48.18 to 77.54 nm, and for trigonella extract, 27.91 to 40.94 nm. In the FT-IR spectra of IONPs with and without plant extract, a strong peak appeared at 699 cm⁻¹ for FeO NPs using trigonella extract and 655 cm⁻¹ using tomato extract. Antibacterial activity of IONPs was determined by growth inhibition zones of the gram-negative bacteria Klebsiellapneumonia and gram-positive bacteria Staphylococcus aureus. The growth inhibition zones for FeO NPs using trigonella extract were 42 and 47 mm, respectively. The zones for FeO NPs using tomato extract were smaller (30 mm and 35 mm, respectively). These NPs may be effective in healing infections caused by these bacteria.

摘要

氧化铁纳米粒子 (IONPs) 是通过将新植物（葫芦巴和番茄）的提取物与氯化铁盐 (FeCl ₃ ) 结合，通过简单的化学方法在 200°C 下 2 小时合成的。提取物中的生物分子在转化 FeCl _{3中起重要作用}FeO NPs 具有抗菌性能。通过 X 射线衍射 (XRD)、场发射扫描电子显微镜 (FE-SEM) 和傅里叶变换红外光谱 (FT-IR) 对 IONP 进行了表征。XRD 揭示了使用葫芦巴提取物制成的 Fe3O NPs 的微晶尺寸为 17 nm，具有体心立方 (BCC) 结构 (wüstite) 相。使用番茄提取物合成的 Fe3O NPs 为 41 nm，衍射峰显示具有优异晶体质量的 BCC 结构相。FE-SEM 图像表明 Fe ₂ O _{3的平均晶粒尺寸}不使用任何植物提取物的波长约为 31.36 至 125.5 nm，而使用番茄提取物的 Fe3O NPs 约为 48.18 至 77.54 nm，而三角藻提取物的波长约为 27.91 至 40.94 nm。在具有和不具有植物提取物的 IONP 的 FT-IR 光谱中，使用三角蕉提取物的 FeO NPs 和使用番茄提取物的 655 cm ^-1出现一个强峰在 699 cm ^-1处。IONPs 的抗菌活性由革兰氏阴性菌肺炎克雷伯菌和革兰氏阳性菌金黄色葡萄球菌的生长抑制区确定. 使用 trigonella 提取物的 FeO NPs 的生长抑制区分别为 42 和 47 mm。使用番茄提取物的 FeO NPs 的区域更小（分别为 30 毫米和 35 毫米）。这些 NPs 可能有效治愈由这些细菌引起的感染。