Genome editing for plant research and crop improvement,Journal of Integrative Plant Biology

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Genome editing for plant research and crop improvement
Journal of Integrative Plant Biology ( IF 9.3 ) Pub Date : 2020-12-24 , DOI: 10.1111/jipb.13063
Xiangqiang Zhan ₁ , Yuming Lu ₂ , Jian-Kang Zhu _{2,

3} , Jose Ramon Botella ₄

Affiliation

The advent of clustered regularly interspaced short palindromic repeat (CRISPR) has had a profound impact on plant biology, and crop improvement. In this review, we summarize the state‐of‐the‐art development of CRISPR technologies and their applications in plants, from the initial introduction of random small indel (insertion or deletion) mutations at target genomic loci to precision editing such as base editing, prime editing and gene targeting. We describe advances in the use of class 2, types II, V, and VI systems for gene disruption as well as for precise sequence alterations, gene transcription, and epigenome control.

中文翻译：

用于植物研究和作物改良的基因组编辑

成簇规则间隔短回文重复序列 (CRISPR) 的出现对植物生物学和作物改良产生了深远的影响。在这篇综述中，我们总结了 CRISPR 技术的最新发展及其在植物中的应用，从最初在目标基因组位点引入随机小 indel（插入或缺失）突变到精确编辑，如碱基编辑，主要编辑和基因打靶。我们描述了使用 2 类、II 型、V 型和 VI 型系统进行基因破坏以及精确序列改变、基因转录和表观基因组控制的进展。

更新日期：2021-01-27

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