Exposure to childhood trauma increases the risk of tobacco use during adolescence. Recent studies have also reported potentially increased vulnerabilities to electronic cigarette (e‐cigarette) use among youth with a history of childhood trauma. While empirical evidence supporting the relationship between childhood trauma and adolescent e‐cigarette use is emerging, few effective preventive interventions are available to curb e‐cigarette use among adolescent victims of childhood trauma. This article reviews current evidence with respect to how childhood trauma could increase risk for nicotine dependence and e-cigarette use in adolescent populations. Furthermore, this paper describes the development, design, and implementation of Rise Above (RA), a randomized, controlled trial of a trauma-informed, e‐cigarette preventive intervention. Lessons learned are also discussed, including the challenges of implementing evidence-informed prevention work within communities vulnerable to traumatic events.

暴露于儿童期创伤会增加青春期吸烟的风险。最近的研究还报告说，有童年创伤史的青年人使用电子烟（电子烟）的脆弱性可能增加。虽然支持儿童创伤与青少年电子烟使用之间关系的经验证据不断涌现，但很少有有效的预防干预措施可遏制儿童创伤青少年受害者中的电子烟使用。本文回顾了有关童年创伤如何增加青少年人群尼古丁依赖和使用电子烟风险的最新证据。此外，本文还介绍了Rise Above的开发，设计和实现（RA），一项针对创伤知情的电子烟预防干预措施的随机对照试验。还讨论了所学到的经验教训，包括在易受创伤事件影响的社区内开展循证预防工作的挑战。