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Induced pluripotent stem cell line (ZZUNEUi011-A) derived from peripheral blood mononuclear cells (PBMCs) of a healthy 27-year-old female individual
Stem Cell Research ( IF 0.8 ) Pub Date : 2020-12-24 , DOI: 10.1016/j.scr.2020.102139
Wanrong Fu 1 , Mengyu Wang 1 , Yangyang Liu 1 , Mengduan Liu 1 , Lu Wang 1 , Liang Hu 1 , Xiaoyan Zhao 1 , Zhongren Ding 1 , Xiaowei Li 1 , Jianzeng Dong 2
Affiliation  

In this study, we report a human induced pluripotent stem cell (iPSC) line from a healthy 27-year-old female individual using non-integrative Sendai viral reprogramming technology. The cell line expresses stemness markers, exhibits a normal female karyotype, and can differentiate into three germ layers in vivo. This iPSC line from a healthy individual provides a control group for studying disease mechanisms, drug screening, and toxicity testing.



中文翻译:


源自 27 岁健康女性个体外周血单核细胞 (PBMC) 的诱导多能干细胞系 (ZZUNEUi011-A)



在这项研究中,我们使用非整合仙台病毒重编程技术报告了来自一名健康 27 岁女性个体的人类诱导多能干细胞 (iPSC) 系。该细胞系表达干性标记,表现出正常的雌性核型,并且可以在体内分化成三个胚层。来自健康个体的 iPSC 系为研究疾病机制、药物筛选和毒性测试提供了对照组。

更新日期:2020-12-28
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