Induced pluripotent stem cell (iPSC) line HUi002-A was reprogrammed from skin fibroblasts via non-integrating, virus free self-replicating RNA. Skin fibroblasts from a 53-year-old male Caucasian, non-familial Parkinson's disease patient, idiopathic (clinical summary confirmed Parkinson's disease) was obtained from the Coriell Institute (AG20442). Generated iPSCs were characterized and pluripotency was confirmed.

中文翻译：

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使用自复制RNA载体从特发性非家族性帕金森病患者中建立人诱导的多能干细胞系

通过非整合的，无病毒的自我复制RNA，从皮肤成纤维细胞对诱导型多能干细胞（iPSC）系HUi002-A进行了重新编程。一名53岁男性，非家族性帕金森氏病患者的皮肤成纤维细胞是特发性的（经临床总结证实为帕金森氏病）是从科里尔研究所（AG20442）获得的。表征生成的iPSC，并确认了多能性。